
Parker Hannifin USP Class VI Elastomers
Parker Hannifin USP Class VI elastomer materials are designed for sealing applications used in pharmaceutical manufacturing, biotechnology, medical devices, laboratory systems, and high purity processing environments requiring biocompatibility and material compliance. These compounds are commonly used in O-rings, gaskets, sanitary seals, diaphragms, tubing seals, custom molded rubber parts, and fluid sealing systems where cleanliness, extractable control, and sterilization resistance are critical. USP Class VI materials are frequently specified for pharmaceutical processing equipment, medical fluid handling systems, clean room applications, and sanitary process systems.
Canyon Components supplies high quality equivalents to many Parker USP Class VI elastomer compounds used in medical, pharmaceutical, and high purity industrial applications. Our team supports replacement O-rings, gaskets, sanitary gaskets, and custom molded sealing components manufactured from USP Class VI EPDM, Silicone, FKM, FFKM, and specialty elastomer materials. We also assist with material selection, clean room manufacturing support, and compliance documentation for regulated sealing applications.
Common names include: USP Class VI elastomers, medical grade rubber compounds, pharmaceutical sealing materials, biocompatible elastomers
Trade names include: Parker®, Viton™, Silicone, EPDM, Canrez®, Parofluor™

FKM O-rings from Canyon Components providing excellent chemical, heat, and compression resistance in critical sealing applications.
Parker Hannifin Materials Available
This table shows many of our standard materials and links out to our O-ring store. Get in touch with us if you need a custom gasket, custom molded part, or non-standard geometry!
Filter by
Temperature Search (°C)
Durometer
Size Search

___X____
Features of Parker Hannifin USP Class VI Materials
- These materials are commonly used in O-rings, sanitary gaskets, diaphragms, tubing seals, and custom molded parts exposed to sensitive process media
- Many USP Class VI compounds provide excellent resistance to cleaning chemicals, sterilization cycles, and high purity fluid systems
- Specialized compounds are available with low extractables, low outgassing, and high purity processing characteristics
- Many materials also support FDA, NSF 51, ISO 10993, and sanitary processing requirements depending on compound selection
- High purity Silicone, EPDM, FKM, and FFKM compounds are available for static and dynamic sealing applications
- Canyon Components supplies equivalent USP Class VI sealing materials with strong availability, engineering support, and rapid lead times
Limitations of Parker Hannifin USP Class VI Materials
- Certain high purity compounds may have reduced abrasion resistance in aggressive dynamic applications
- Steam sterilization and repeated CIP or SIP cycles may reduce the service life of some elastomer materials
- Some USP Class VI materials prioritize purity and extractable control over mechanical durability
- High performance USP Class VI FFKM compounds may significantly increase cost compared to standard industrial elastomers
- Not all medical grade compounds are suitable for continuous exposure to aggressive solvents or hydrocarbons
Please consult a Canyon Components Engineer about your specific application and we will use our decades of experience to formulate a solution that fits your need.
Pharmaceutical and Medical Applications for USP Class VI Materials
USP Class VI elastomers are widely used in regulated systems requiring high purity sealing performance and material traceability. These materials are commonly installed in pharmaceutical manufacturing systems, biotechnology equipment, sanitary processing systems, laboratory instruments, medical fluid handling systems, and clean room equipment. Material selection depends on sterilization method, chemical exposure, process temperature, extractable requirements, and regulatory compliance.
Canyon Components supports pharmaceutical manufacturers, biotech companies, medical device manufacturers, and industrial processing customers with Parker equivalent USP Class VI O-rings, gaskets, and custom molded sealing components. Parker compound references and material information can be found in the Parker material offering guide and Parker O-Ring Handbook.
Pharmaceutical Processing Equipment
USP Class VI O-rings and gaskets are commonly used in reactors, mixers, filling systems, transfer systems, and fluid handling equipment used in pharmaceutical manufacturing.
Biotechnology Systems
Biotech systems require low extractable elastomer materials capable of maintaining sealing performance while minimizing contamination risk.
Sanitary Fluid Handling
Sanitary gaskets and seals used in hygienic processing systems commonly utilize USP Class VI EPDM, Silicone, and FFKM materials.
Medical Devices
Medical equipment and diagnostic systems frequently use biocompatible elastomer materials for fluid sealing and environmental sealing applications.
Clean Room Manufacturing
USP Class VI elastomers are often manufactured and packaged in clean room environments to support semiconductor, pharmaceutical, and medical applications.
Please consult a Canyon Components Engineer about your specific application and we will use our decades of experience to formulate a solution that fits your need.
All Other Parker Material Types Available
All Parker Materials
Canyon Components supplies Parker® O-rings and custom parts in premium materials like FFKM, Silicone, EPDM, NBR, and Polyurethane. Available in AS568, Metric, and custom sizes for industrial, aerospace, medical, and chemical processing applications—all with competitive pricing and fast lead times.
Parker Hannifin Parofluor FFKM
Explore Parker Hannifin Parofluor FFKM materials for extreme chemical resistance and high temperature sealing. Compare Parofluor with Canrez® FFKM for O-rings, gaskets, and custom parts in demanding applications.
Parker Hannifin Viton™ Fluorocarbon Elastomers
Parker Hannifin Viton™ Fluorocarbon Elastomers available now! Contact our engineering team for assistance selecting Parker Hannifin Viton™ materials or qualified equivalents for your sealing application.
Parker Hannifin Polyurethane
Explore Parker Hannifin polyurethane materials for O-rings, gaskets, and custom parts requiring excellent abrasion resistance and strength. Compare Parker polyurethane compounds with high-quality Canyon Components equivalents.
Parker Hannifin Aflas®
Explore Parker Hannifin Aflas® materials for O-rings, gaskets, and custom parts designed for steam, amine, and chemical resistance. Compare Parker Aflas® compounds with high-quality Canyon Components equivalents.
Parker Hannifin Silicone
Explore Parker Hannifin silicone materials for O-rings, gaskets, and custom parts designed for flexibility across extreme temperatures. Compare Parker silicone compounds with high-quality Canyon Components equivalents.
Parker Hannifin Fluorosilicone
Explore Parker Hannifin Fluorosilicone materials for O-rings, gaskets, and custom parts designed for fuel resistance and low temperature flexibility. Compare Parker fluorosilicone compounds with high-quality Canyon Components equivalents.
Parker Hannifin EPDM
Explore Parker Hannifin EPDM materials for O-rings, gaskets, and custom parts designed for water, steam, and weather resistance. Compare Parker EPDM compounds with high-quality Canyon Components equivalents.
Parker Hannifin NBR
Explore Parker Hannifin NBR materials for O-rings, gaskets, and custom parts offering excellent oil and fuel resistance. Compare Parker nitrile compounds with high-quality Canyon Components equivalents for industrial applications.
Parker Hannifin HNBR
Explore Parker Hannifin HNBR materials for O-rings, gaskets, and custom parts requiring excellent heat, oil, and abrasion resistance. Compare Parker HNBR compounds with high-quality Canyon Components equivalents for demanding applications.
Parker Hannifin ACM
Explore Parker Hannifin ACM materials for O-rings, gaskets, and custom parts designed for heat and oil resistance in automotive and industrial applications. Compare Parker ACM compounds with high-quality Canyon Components equivalents.
Parker Hannifin Neoprene
Explore Parker Hannifin Neoprene materials for O-rings, gaskets, and custom parts offering balanced oil, weather, and ozone resistance. Compare Parker Neoprene compounds with high-quality Canyon Components equivalents.
Parker Hannifin Butyl
Explore Parker Hannifin Butyl materials for O-rings, gaskets, and custom parts requiring low gas permeability and chemical resistance. Compare Parker Butyl compounds with high-quality Canyon Components equivalents.
Back to Elastomers Hub










